Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
Eighty medical students from across the US and Puerto Rico are selected for a six-week summer experience to introduce them to clinical research early in their careers. The program aims to develop the next generation of clinical investigators equipped to engage communities and improve participation in clinical trials.
A team of researchers has discovered large droplets of proteins known as condensates near inactive chromosome regions within the cell nucleus that are a feature of some cancer cells. The newly found condensates store excess gene-activating protein TEAD1, regulating its activity and preventing toxicity to the cell.
The collaboration aims to expand research and clinical program development in spinal cord stimulation, pairing it with intensive activity-based training to improve movement, mobility, and other functions. This effort will help move evidence-based practices into broader clinical use, benefiting people living with a spinal cord injury.
Researchers identified age-related genetic changes in microglia that may drive inflammation and neurodegeneration in Alzheimer's disease. Cancer-associated mutations were found in genes commonly linked to clonal hematopoiesis, promoting inflammatory activity.
Baylor College of Medicine researcher Dr. Jimmy Holder and his team will join the ARIA IMPACT Network to accelerate clinical trial readiness and implementation for promising therapies on autism. The collaboration aims to better understand how autism develops and changes over time in children with profound autism.
This Brazilian adult study explores the association between mental health, dermatology-related quality of life, and probiotic intake. Women were found to have higher anxiety, depression, and stress levels than men, with strong positive correlations among these conditions.
Researchers found that certain unicellular organisms can stick together when fed specific bacteria, revealing a possible mode of early animal evolution. This discovery sheds light on how cells began to cooperate and reproduce as multicellular organisms billions of years ago.
Gravastars may form when a star collapses under its own mass, triggering the creation of a mini universe with dark energy. This equilibrium stabilizes the object, preventing it from becoming a black hole.
A study led by UC Riverside highlights the importance of rigorous participant verification procedures in online health research to maintain data quality. Researchers found that combining automated screening, human review, and participant verification can substantially improve confidence in online research findings.
A study predicts climate change will trap air pollutants over coastal areas, increasing health risks for millions in Barcelona. Ozone concentrations are projected to rise substantially along the coastline by 2100.
A new model proposes a comprehensive framework for understanding altitude-related illnesses as interconnected manifestations of a common underlying process. The Hypoxia Stress-induced Multi-organ Injury (HSMI) framework emphasizes the widespread biological responses triggered by oxygen deprivation, affecting organs over time.
Dr. Milad Alucozai joins C-Path's Board of Directors with extensive experience in U.S. biotechnology and startup community, including founding and investing in companies like Pamir Ventures and Revalia Bio. His appointment reflects the organization's commitment to integrating emerging biotechnology into its global mission.
The poll found that trust in CDC health recommendations declined from 77% in spring 2025 to 50% in the last year, with deep partisan divides and demographic groups affected. Trust in state and local public health agencies also fell, but not as dramatically, with state and local health departments being more trusted than federal agencies.
A new AI algorithm has been developed to screen for underlying heart failure in GP clinics or at home, aiming to reduce waiting times and save NHS costs. The test uses a routine Electrocardiogram recording to detect changes in the heart's structure and pumping functions.
A study at the Federal University of São Paulo found that only a fraction of copper and magnesium from Brazil nuts and cashews is absorbed by the human body. The researchers used an in vitro gastrointestinal digestion assay to assess bioavailability, which differed from bioaccessibility.
The FDA has accepted Genentech's supplemental Biologic License Application for atezolizumab, supported by phase III ATOMIC trial results. The trial showed a 50% reduction in cancer recurrence or death and 86.3% disease-free survival rate.
A team of researchers used large language models to study the effects of stress, sadness, and anxiety, finding that the models can reproduce human-like emotional responses. The study's results suggest that these models could be a valuable tool for understanding and addressing mental health conditions.
Researchers at MSK discovered that tumors with low levels of NF2, a tumor suppressor gene, are less likely to respond to immunotherapy. They also found that combinations of VEGFR-TKIs and immunotherapies can be effective but have limited long-term benefits due to paradoxical effects of hypoxia on treatment response.
Researchers at the University of Washington are using AI and quantum computing to design new materials with unique properties, such as superconductivity and entanglement. The tools are helping to power the growing field of quantum computing and could lead to breakthroughs in energy-efficient electronics.
Researchers found that people tend to move counterclockwise when walking, influencing crowd behavior and collective patterns. This individual inclination helps explain certain phenomena, offering a new perspective on understanding crowd dynamics.
A new study reveals that employer points systems, which penalize workers for absences regardless of reason, are strongly associated with presenteeism and undermine public health benefits of paid sick leave laws. Workers in the US who were subject to these systems were more likely to show up to work while sick.
Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics its complex mechanical behavior. The study could help researchers better understand valve disease and develop new treatment approaches.
A controversial cooling strategy to shield Earth from sun's rays could offer unequal protection for oceans and communities, leaving 25-75% of seas at risk from overheating. Researchers used computer simulations to forecast marine heat waves under future scenarios with and without solar geoengineering.
Boston Children's Hospital has been awarded up to $17.25 million to participate in the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network, an international effort aimed at speeding up the development of urgently needed treatments for children with profound autism and related neurodevelopmental disabilities...
The ACM Technology Policy Council's TechBrief examines agentic AI's legal liability, security risks, and workforce impacts. Existing frameworks fall short in addressing accountability questions, highlighting the need for defined authentication and delegation standards, robust audit trails, and sector-specific guidance.
Researchers found that 95% of animal species vocalize at a rate between 0.45 and 4.99 Hz, with a peak at 2.8 Hz, suggesting a shared ancient constraint across species. This universal tempo may facilitate communication between species.
Researchers from the University of Calgary and international collaborators explored the zoonotic potential of CWD in controlled laboratory settings. The study found that infectious prions can still be present and transmissible even without obvious clinical signs, highlighting the need for continued surveillance and research.
A new study published in Clinical Infectious Diseases found that metformin reduced the risk of clinician-diagnosed long COVID by 50% when administered during acute COVID-19 infection. The study, which enrolled nearly 3,000 adults, showed improved long-term outcomes and no safety concerns.
A new soft gripper designed by WVU researcher Anand Mishra can accurately gauge the size, curvature, color, and ripeness of fruits like strawberries and avocados. The gripper's quick inspections and harvesting capabilities can reduce spoilage and lower supply chain costs.
Researchers at MPI-SusMat discovered that adding specific metal oxides as catalytic precursors can double the reduction kinetics of hydrogen-based metal production, allowing for reduced energy use. This breakthrough enables lower reduction temperatures, shorter processing times, and reduced energy consumption.
Researchers measured electron velocities and concentrations in low-Earth orbit to map the travel pattern of solar energy from magnetic reconnection to its interactions at cusps. The study provides new insights into solar effects on Earth that drive space weather.
The Temple Family Thriving Program integrates caregiver and early childhood support into prenatal and postpartum care to strengthen parent-child bonds and promote healthy development. The program aims to reduce risk factors associated with child abuse and neglect by addressing caregiver stress and promoting positive parenting practices.
The Global Conference on Gerophysics brought together researchers from various disciplines to develop predictive models of aging. Key findings include the application of physical principles, such as thermodynamics and network theory, to biological systems. The conference highlighted the importance of collaboration between theory and ex...
A scientific team has developed an AI-powered approach to solve a practical problem in materials science by locating missing atomic positions in otherwise known structures. By using an adapted open-source model called XtalPaint, researchers can reconstruct accurate crystal representations with a success rate of 97%.
A new preclinical study by Amsterdam UMC researchers overturns a key assumption in the biological pacemaker field. They show that transcription factor TBX18 does not generate true pacemaker activity, while ion channel Hcn2 produces robust pacemaker function in the heart.
A new study found that plants can reveal recent PFAS contamination linked to airborne deposition, suggesting direct exposure from the atmosphere rather than uptake through roots alone. The research suggests that vegetation can serve as a valuable tool for tracking emerging environmental contaminants and complement traditional soil-base...
A study in mice reveals that slow fluctuations in hypothalamic histamine neurons act as a dynamic gate, making stored memories more or less accessible when a cue arrives. Histamine neuron activity helps prepare the brain before the cue appears, increasing memory-guided licking responses.
Researchers at HKUST have elucidated the mechanism of water facilitating reactions in interfacial polymerization, enabling predictable microcapsule design. They also developed an AI-driven platform for rational design of microcapsules with tailored properties.
Research found that companies with more independent board members adjust CEO compensation more quickly towards optimal levels. Boards make calculated trade-offs and consider costs and benefits before changing pay structures.
A team of researchers at Institute of Science Tokyo found that Raman optical activity can occur in nonmagnetic, centrosymmetric crystals with ferroaxial order, which introduces an internal directional property. This effect depends on the orientation of the crystal and is linked to the direction of internal rotational order.
Remote monitoring approaches did not increase home time but reduced it for those 65 years and older, supporting tailored care after acute infections. The findings suggest reevaluating remote monitoring to align with patients' needs and desires.
A clinical trial tested four remote monitoring approaches against usual care and found that none outperformed usual care in reducing readmissions. The study highlights the importance of studying real-world care models to optimize outcomes.
Researchers warn that open-source AI could increase environmental pressures, deepen technological inequalities, and spread misinformation. To mitigate these risks, the authors propose four governance actions to ensure AI contributes positively to the Sustainable Development Goals.
Researchers discovered that intestinal obstruction affects feeding and sleeping behavior in fruit flies, causing lethargy and death. The study found a genetic defect responsible for intestinal blockage, leading to the formation of a 'Reinger's knot' that blocks the intestine.
Dr. Samantha Parker Kelleher and researchers will examine the role of postpartum hypertension on recurrent hypertensive disorders of pregnancy, such as preeclampsia and gestational hypertension. The team aims to identify ways to decrease HDP rates among mothers and develop new prevention strategies.
Extracellular vesicle-encapsulated microRNAs (EV-miRNAs) form a precise communication network for organ crosstalk, mediating immune regulation and disease outcomes. EV-miRNAs display organ tropism, influencing tumor growth, anti-tumor immunity, and inflammation.
A new survey by the Annenberg Public Policy Center finds Americans sharply divided over the use of fluoride in public drinking water. Supporters of the Make America Healthy Again movement are notably more skeptical about fluoridation's health effects, while a majority trust the American Dental Association's stance on its safety.
IOP Publishing integrates IPregistry.org to deliver faster and more accurate IP authentication for libraries worldwide. The integration enables automated IP address updates, reducing the risk of authentication errors and saving librarians administrative time.
Researchers at the University of Groningen found that a clinically approved asthma drug can restore access to social memories disrupted by sleep deprivation. In a study, mice who were sleep deprived after meeting other mice couldn't recognize them later, but the drug roflumilast allowed them to recall their social encounters.
A new study investigated the effects of ornidazole, an antimicrobial drug, on male fertility. Ornidazole was found to reduce sperm count and motility, as well as disrupt seminiferous tubule structure, in both mouse and human models.
Astronomers have discovered a new millisecond pulsar named PSR J1810−0623, featuring an exceptionally circular orbit. This discovery provides valuable information about binary evolution processes and the Galactic magnetic field structure.
A study in Dutch birth cohorts found early pregnancy temperature exposure associated with changes in fetal size, with colder temperatures linked to smaller crown-rump length at 12 weeks. Higher temperatures showed stronger associations during early pregnancy.
Researchers identify CLASS 3G subtype of EGFR mutation associated with limited response to targeted drugs. This structural subtype alters protein shape, reducing treatment efficacy and allowing for more effective combination therapy.
A Delft University of Technology breakthrough integrates perception, decision-making, and execution into a single framework. The model detects hazardous situations, predicts traffic evolution, and determines effective avoidance strategies, with realistic braking reaction times and human-like behavior.
Researchers successfully generated rat-derived kidneys in mice using interspecies blastocyst complementation, demonstrating potential for growing transplantable human organs in larger animals. The study represents an important step toward addressing global kidney shortages.
A novel HfO2-SiBOC ceramic has been designed and synthesized with a density of 2.49 g/cm3, significantly lower than traditional ultra-high temperature ceramics. The ceramic exhibits outstanding ablation resistance under 2000°C oxyacetylene flame for 300 s, making it a promising material for ultra-high temperature applications.
Researchers have identified a key muscle hormone, musclin, that helps clear dead cells and treat periprosthetic joint infections. Musclin triggers macrophage metabolism shifts, boosting efferocytosis capacity and breaking the cycle of inflammation.
A study of 6,165 Salmonella samples identified 128 types of toxins, including 45 previously unknown. The toxins act in competition among microorganisms and may inspire antibiotic development and biotechnological applications.
A White House announcement on treating autism with leucovorin and against acetaminophen during pregnancy led to significant increases in internet searches for these topics. Nearly 1 million additional searches for leucovorin were recorded, alongside over 4 million searches for acetaminophen.
A team of researchers from The University of Osaka has developed a new approach for depth reconstruction from defocus, estimating distances by analyzing blur in an image. Their method combines a coded-aperture camera with diffusion-model-based AI to accurately estimate depth and produce high-quality images.