Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
The study reconstructs thalamic development, identifying two major cell lineages that diverge early and distinct genetic programmes, and pinpointing the gene Sp9 as essential for visual neuron identity.
Researchers at ETH Zurich have developed a method to archive RNA molecules in cells, enabling the examination of past gene activity and short-lived responses in immune and stress cells. This breakthrough allows for the investigation of rare events in cells and has potential applications in cancer research.
A recent analysis reveals a decline in low-risk prostate cancer diagnoses and increased use of active surveillance, indicating a shift away from overtreatment. This change is attributed to growing concerns about overdiagnosis and overtreatment, leading to reduced treatment among patients with low-risk cancers.
A study by Osaka Metropolitan University found that Japan's Depopulated-Area-Designation policy does not reverse or stabilize population decline in small and medium-sized cities. After 15-20 years, designated municipalities show significant population decline, similar to non-designated municipalities.
Chiba University and INPA will engage in international joint research to contribute to science promoting human health and development of human resources. The five-year partnership will focus on immunology, infectious diseases, and sustainable resource utilization.
A large study found that emergency department visits and hospitalizations for substance use among young mothers increased by 5% per year, similar to rates among childless women. Young mothers under 25 drove these increases, with rates growing four times faster than among other females. The study highlights the need for better support s...
A team of researchers developed a unified framework to detect and explain vulnerabilities in smart contracts. Their tool, HCA-SGNN, analyzes contracts and identifies exact flaws, providing detailed explanations. This framework has the potential to improve security audits and developer tools in blockchain-based financial services.
Researchers investigate Japan's first climate transition bonds, finding that investors demand higher returns due to uncertainty about environmental improvements. The study highlights the importance of clear transition plans and transparent reporting to strengthen investor confidence and reduce financing costs.
Researchers at the Center for Astrophysics | Harvard & Smithsonian have developed Lumina, the largest and most detailed simulation ever created of the early universe. The simulation recreates how ordinary matter, dark matter and radiation interacted during the universe's first 2 billion years, giving scientists a powerful new tool ...
Researchers at the University of Johannesburg found that airborne ESKAPE bacteria can survive exposure to first-line and last-resort antibiotics, making them highly resistant to treatment. The study's findings highlight the need for improved infection control measures in high-risk areas, where HIV and TB infection rates are high.
The Stanford Natural Capital Alliance and IDB launched new resources to support applications of natural capital approaches worldwide. The resources include a free MOOC and online Implementation Toolkit, distilling lessons from the People, Planet, Prosperity project.
Patients with KRAS-mutated lung cancer treated with divarasib lived a median of 18 months and experienced improved disease control compared to standard therapies. Divarasib reduced the risk of cancer progression by 42% and death by 44%, with fewer severe side effects reported.
The London Register of Subsurface CO₂ Storage reports a record 43.6 million tonnes of CO₂ stored in 2024, with cumulative storage reaching 421.7 million tonnes over the past three decades. The Register tracks geological CO₂ storage, which is expected to become a leading technology for mitigating climate change by mid-century.
New research found that SGLT2 inhibitors reduce all-cause mortality and major adverse kidney events by 18% and 22%, respectively, in adults aged 80 years or older with CKD. However, these medications may also increase the risk of specific cardiac events and acute kidney injury in this demographic.
A Rutgers study found that 1 in 3 young adults (18-29 years) use AI for substance-use information, primarily seeking risks and consequences. The study highlights the need for research on how young adults interpret and understand AI outputs on substance use, with implications for public health.
A new study reveals that airflow can cool UV-C lamps, altering their output and reducing airborne particle exposure time. Researchers found that higher-power lamps maintained stable output, while lower-power lamps were more sensitive to airflow and temperature fluctuations.
A new immunotherapy combination extends survival in patients with advanced endometrial cancer, with patients receiving durvalumab plus olaparib living almost one year longer than those treated with chemotherapy alone. The treatment was particularly effective for patients with mismatch repair proficient tumors, who have traditionally ha...
A new EU project, TETTRIX, aims to integrate European taxonomic data, tools, and expertise to inform biodiversity conservation and ecosystem resilience. The project will develop innovative tools and services to advance species identification and strengthen the connection between taxonomic knowledge and policy-making.
A Keck School of Medicine of USC research study found that an experimental drug called cinaciguat reverses the effects of aging in the liver, potentially lowering the risk of Alzheimer's disease and heart disease. The treatment also normalizes amyloid beta and LDL levels, which are associated with Alzheimer's and atherosclerosis.
Researchers found that commonly used kidney function tests, such as estimated GFR, significantly underestimate chronic kidney disease in patients with cancer. This discrepancy can lead to inadequate treatment decisions, including dose adjustments for anticancer therapy. The study suggests that errors in GFR estimation may contribute to...
US-Mexico border counties experience disproportionately elevated rates of death from chronic kidney disease (CKD), with reduced availability of nephrologists. The findings highlight a growing kidney health disparity, with counties having the lowest nephrologist density having substantially higher mortality rates.
The Phase 2 BESTOW trial shows that tegoprubart preserves kidney function and improves quality of life in kidney transplant recipients. Tegoprubart-treated patients had greater kidney function benefits and improved health-related quality of life compared to tacrolimus-treated patients.
A significant spike in suicidal thoughts, planning, and attempts among older US adults was found in the years following the COVID-19 pandemic. The study's findings suggest that traditional risk factors may not be the only factors at play, and that a broader risk assessment approach is needed to identify older adults at risk.
Researchers analyze a new sediment core in southern Sweden, finding microspherules and platinum-rich nanoparticles suggesting an extraterrestrial event triggered the Younger Dryas cooling. The study expands the European archive, separating the Laacher See eruption, Younger Dryas Boundary, and cooling event.
Kessler Foundation was recognized as one of America's Best Workplaces for 2027, highlighting its collaborative environment that supports professional growth. The foundation's commitment to employee growth and development is reflected in its recognition as a Best Place to Work for Women in 2026.
Everleap Fertility will deliver 19 scientific presentations at the ASRM Annual Scientific Congress & Expo, exploring topics like endometrial thickness and cycle cancellation, and the impact of maternal obesity on embryonic aneuploidy. The research aims to improve clinical processes and patient outcomes across the fertility industry.
Researchers at UC San Diego used new airborne lidar to map cliff erosion and retreat, finding that change was highly uneven along the California coast. Hotspots were identified in Central and Northern California, with some areas experiencing retreat rates exceeding 70 feet per year.
A computational model generates a digital twin of the human thorax to predict the path of light radiation and tailor noninvasive therapies to each patient's anatomy. This allows for personalized dosimetry and a more effective therapeutic response in the treatment of pneumonia.
Small cell lung cancer cells are equally dependent on cysteine, but react differently when deprived of it. Cells with low ASCL1 levels die via ferroptosis, while those with high ASCL1 levels are protected and can evade treatment. The study provides a potential starting point for new therapeutic strategies.
A new vaccine has shown promise in generating an immune response against KRAS mutations in pancreatic cancer, with patients who developed stronger immune responses showing longer disease-free survival. The vaccine targets seven common KRAS mutations and has the potential to improve treatment outcomes for patients with pancreatic cancer.
The study found that Nematostella carries eight of the ten proteins humans use to pair and align meiotic chromosomes, making it a promising system for understanding human fertility. The sea anemone's proteins show unexpected flexibility in their roles, revealing new insights into meiosis and its potential impact on fertility.
Researchers found that larger movements improve learning on similarity-based categories, but not on rule-based categories. The study suggests that movement shapes learning itself, rather than just responding to visual stimuli.
Cancers can evade chemotherapy by entering a 'zombie-like state' called premature senescence, which tricks the immune system into helping malignant cells. This phenomenon allows tumours to acquire extra oxygen and nutrients, making them more resistant to chemotherapy.
A study discovered that an ancient viral remnant in chimpanzee DNA silences a key gene, LINC00662, which is active in humans and plays a role in early brain development. This finding highlights the importance of understanding gene regulation and its potential link to brain diseases.
Researchers at the Centre for Genomic Regulation have discovered a six-gene scoring system that reliably predicts patient survival in acute myeloid leukemia. The PHFScore system, which combines the activity of six genes, can divide patients into groups with sharply different survival prospects.
A new study reveals evidence of east-west genetic exchange and long-term population continuity in southwestern Europe, linking populations across thousands of years. Genetic data from rare human remains and cave sediments provide key insights into the Gravettian culture.
Researchers at the University of Melbourne found that knowing the Pacific Ocean's state at the beginning of a forecast can provide valuable clues about a forecast's reliability one year later. Forecasts initiated during La Niña conditions consistently performed well, while those starting from neutral conditions were less reliable.
Researchers at the University of Pennsylvania have developed a novel insulator using stacked Mylar sheets, which combine strong thermal insulation with mechanical durability. The material, called hybrid layered insulating film stacks, has been tested in a vacuum and shown to maintain its thermal performance under compressive stress.
The TOSYMA study found that tomosynthesis detected significantly more invasive breast cancers than mammography, with a 24% lower rate of interval cancers over two years. This suggests that tomosynthesis may be more effective in preventing aggressive interval cancers.
Farell Keiser, a high school student, published a paper in Physical Review B as the first author, showcasing his substantial contribution to the field of terahertz research. His work focused on zinc telluride and demonstrated a more accurate physical description of terahertz generation in the material.