Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
The Biophysical Society strongly opposes the Office of Management and Budgets' proposed rule, which centralizes control over regulations under the White House. This overhaul could have a chilling effect on scientific research, as federal agencies with subject matter expertise would lose individual oversight.
Researchers used patient-derived xenograft (PDX) models to study deadly DNA loops in cancer cells. They found significant similarities between human tumor samples and PDX models, including consistent presence of extra copies of oncogenes. These findings suggest that ecDNA-positive tumor cells may drive tumor growth and recurrence.
A University of Bristol team has developed an AI system that can automatically find, name, and follow individual animals in footage, saving thousands of hours for researchers. The system, part of the SA-FARI project, uses a foundational Vision-Language Model to precisely identify objects in images or videos.
A physicist at Mississippi State University has received a prestigious CAREER Award to study stellar explosions and their role in forming elements. The five-year project aims to improve computer models of supernovae and neutron stars, shedding light on the universe's elemental composition.
Dr. Elizabeth Kim, a researcher at Weill Cornell Medicine, has received the 2026 Tri-Institutional Breakout Award for her work on drug targeting of HCN1, an ion channel protein linked to diseases like epilepsy. Her study, published in Nature in 2024, discovered how propofol can restore mutant channels to normal function.
A study of 308 Chinese women aged 15–65 years found that women were perceived to be, on average, 1.6 years older than their actual age. Aging features such as nasolabial folds and skin evenness emerged as major determinants of age perception.
The Ipiranga Museum in São Paulo will utilize 3D laser scanning technology to create a digital model of the renovated building and establish an information management system for preventive maintenance. The project aims to analyze the behavior of the building following restoration work, identify anomalies, and prevent costly interventions.
A new handheld probe using broadband optical spectroscopy (BOS) reliably identifies early stages of necrotizing enterocolitis in premature infants. The noninvasive device measures infrared light reflecting off the intestines and detects color changes indicative of threatened tissue.
Researchers developed an AI system called OCTCube-M that can accurately identify eight different retinal diseases, including age-related macular degeneration. The technology also predicts the progression of severe forms of this condition and can infer health risks beyond the eye.
The study reveals a 250-kilometer-long linear cluster of about 1750 earthquakes marking the edge of the Yakutat microplate as it subducts beneath the North America plate. The new extent places it directly below the apex of curvature of the Alaska range and the Denali fault.
The Journal of Nuclear Medicine has published several groundbreaking studies on targeted radiotherapy approaches for various types of cancer. Researchers have successfully identified tumors using fibroblast activation protein (FAP)-targeting compounds and explored the potential of PET/MRI scans in detecting endometriosis and recurrent ...
Researchers at NINN and SOKENDAI develop a new strategy for synthesizing three-dimensional macrocycles in a square shape, featuring acid responsiveness and recyclability. The method uses an imine bond to create the shape, respond to stimuli, and revert back.
The study reveals that nearly three billion people live in areas with moderate cooling poverty, while 550 million experience severe cooling deprivation. Poor housing and weak healthcare further increase the danger of heat-related illness, particularly among outdoor workers.
Researchers discovered that supergiant deep-sea isopods have a dual survival strategy to cope with nutrient-poor conditions: an enlarged stomach for storing food and extremely low basal metabolic rate. This allows them to thrive in extreme environments.
Researchers introduce a set of universal relations that connect spectrum shapes to wave behavior in one-dimensional disordered systems. The framework reveals a never-before-seen critical state where waves localize differently depending on direction, and shows how it can be tracked using a topological winding number.
UT San Antonio's Jeff Prevost is appointed to the Texas Quantum Initiative Advisory Committee, guiding strategic investment and collaboration to advance the state's leadership in quantum research and technology development. The committee aims to develop a strategic plan supporting the growth of Texas' quantum economy.
A study led by Northwestern University identified a new biological culprit behind cognitive decline in people with HIV: the degradation of protective sugar molecules. Flu drugs preserved these sugar molecules and protected the brain in lab and mouse studies.
The Oeiras Experimenta project, a Living Lab for climate-resilient crops and sustainable food production, has won the 2026 Mariano Gago Ecsite Award. The award recognizes the collaborative work of researchers and citizens in building knowledge relevant to society.
A new approach to managing fatigue in inflammatory arthritis combines physical activity and cognitive behavioral techniques. Digital patient education is shown to be cost-effective and efficient in improving patient outcomes. Caregiver-focused interventions are also crucial in supporting daily functioning and disease management.
A multinational clinical trial found that balanced crystalloid fluid and 0.9% saline are equally safe and effective for treating septic shock in children. The study enrolled over 9,000 children and showed no difference in outcomes between the two IV fluids.
A University of Manchester astronomer led a major international effort to update the long-standing 'post-detection protocols' used in Search for Extraterrestrial Intelligence (SETI). The revised Declaration of Principles marks the first major update in over 15 years, reflecting a media landscape transformed by social media and artifici...
A new study presented at EULAR 2026 highlights the importance of structured cardiac evaluation in systemic sclerosis, particularly for patients with multi-system disease. The research also identified PDE4B as a promising therapeutic target across various tissues and cell subsets, offering potential benefits for patients with early dise...
A new study reveals that the Atacama Desert's hyperarid core became arid 45 million years ago, contradicting previous assumptions. The research team used cosmogenic nuclide dating to analyze quartz clasts and found exceptionally high concentrations of rare isotopes, indicating that surface clasts remained undisturbed for tens of millio...
A study published in JAMA Network Open found that maternal RSV vaccination reduces hospitalization risk in young infants by nearly 70%. The vaccine also showed effectiveness against severe lung infections caused by the virus.
The DIVINE cohort database contains clinical information from 5,813 COVID-19 patients, including characteristics, risk factors, treatments, and outcomes. The data can be used to study disease progression, identify associated factors, and validate predictive models.
A new AI tool, AIDD, combines brain scans with machine learning to accurately diagnose two common forms of dementia. The tool showed near-perfect accuracy in identifying Alzheimer's disease and dementia with Lewy bodies, offering a promising future for clinicians.
A study found that passive AI use can lead to a decline in outcome satisfaction of 21% compared to manual writing, while collaborative AI use showed similar scores. Passive AI use also reduced feelings of ownership and perceived meaningfulness by nearly 20%.
Researchers discover repetitive regions of the human genome, previously considered 'junk DNA', could contribute to cancer development through epigenetic and transcriptional alterations. The study uses advanced sequencing technologies to characterize these regions and their molecular interactions.
Researchers developed a mineralized DNA hydrogel that coordinates immune regulation and sustained bone regeneration. The material promotes healing-friendly macrophage activity while supporting bone-forming stem cells, accelerating bone repair and improving tissue mineralization.
Cellular senescence has emerged as a key biological process linked to aging and age-related disease. Researchers have identified major features of senescence, including stable proliferative arrest and the senescence-associated secretory phenotype (SASP), which can influence inflammation and tissue dysfunction.
Patients described GLP-1 RA therapy as a facilitator of lifestyle change, highlighting the need for standardized guidelines on patient education and clinical support. The quality of care was highly variable, leading to potential expectation management issues around adverse effects and long-term management.
Researchers successfully engineered a novel platinum cluster catalyst that maximizes hydrogen production performance while minimizing platinum usage. The catalyst enables precise control over the number of atoms in each cluster, achieving world-leading hydrogen production per unit of platinum.
A study finds that maternal RSV prefusion F vaccination protects against RSV-associated acute respiratory illness and lowers hospitalization rates among infants under 1 year. The findings support the effectiveness of this vaccine in preventing severe respiratory illnesses.
A new study has overturned longstanding ideas about how germinal centers function, revealing that they are far more selective than once thought. The findings suggest that the immune system ultimately produces stronger antibodies by repeating a noisy, almost random process over and over across many germinal centers.
Researchers at University of Alicante uncover significant evidence of large-scale arms trading and commercial exchange in the western Mediterranean during the late medieval period. The 43 helmets, originally attributed to Roman origin, have been redated to between the late 14th and early 15th centuries.
A multidisciplinary patient organisation provides accessible, person-centred support through professional counselling, offering a non-clinical setting to discuss everyday challenges and work-related issues. The service also offers unique insights into unmet needs, such as medication shortages and administrative barriers.
Researchers developed an interferometric second-harmonic generation imaging approach to identify antiparallel domains and detect hidden structural defects in hBN thin films. The study finds that SHG intensity is closely associated with differences in crystal orientation and destructive interference between domains.
A POSTECH research team developed a haptic device that can operate inside MRI scanners, enabling the measurement of brain activity during VR experiences. The study found that adding tactile feedback increased brain activation in areas responsible for motor control, attention, and cognitive processing.
Scientists have developed a genome engineering platform that enables simultaneous gene knockout, base substitution, insertion, deletion, duplication, and inversion in a single framework. The TRIM platform integrates multiple desirable traits by combining gene knockout with prime editing-based sequence modification.
New research from Griffith University reveals how Florida Governor Ron DeSantis' anti-ESG politics are reshaping financial markets. The study found that fossil fuel companies played a significant role in limiting banks and pension funds' investments in ESG-aligned companies.
A new study reveals that IS110 elements use two RNA-guided pathways to insert donor DNA into target sites, challenging the classical 'cut-out-paste-in' model. The researchers identified a figure-eight DNA intermediate in one pathway and a direct-transfer pathway without forming a conventional intermediate.
Researchers present findings on a novel therapeutic strategy for PsA, using synovial biopsy-driven treatment with biologics targeting IL-17/23 axis. A separate study evaluates the effectiveness of personalized dietary interventions in improving clinical outcomes.
Researchers developed a transistor technology that enables a single device to perform multiple circuit functions simultaneously, simplifying circuit design and increasing data processing speed. The new approach reduces required transistors by 75% and increases data processing speed fourfold.
A new study by Agbonma Onyeka and colleagues demonstrates that Lentinus squarrosulus can be cultivated using locally available agricultural waste, reducing waste management issues and creating a safer alternative protein source. The researchers successfully grew the mushroom on different sawdust species types, producing edible biomass ...
Researchers discovered a previously unknown enzyme system in anaerobic bacteria that converts toxic chloromethane into non-toxic substances. The system, found in species Acetobacterium dehalogenans, has implications for environmental remediation and climate research.
A population-based cohort study found that IIM subtypes differ in incidence, particularly by sex and ethnicity. Automated quantitative nailfold videocapillaroscopy (NVC) model shows superior discriminative capacity for predicting disease activity compared to traditional serum biomarkers.
A landmark review proposes cytoskeletal prestress homeostasis as fundamental biological principle regulating cellular behaviors, including cell stiffness and gene transcription. Dysregulated prestress homeostasis is linked to cellular senescence and cancer metastasis.
A modified culture medium can quickly and affordably detect fidaxomicin resistance in C. difficile infections, saving 201 hours of work and $9,075 per 1,000 patients screened. The new method correctly identifies resistant isolates with 100% sensitivity.
A large Japanese study found that maintaining a healthier profile with lower lifestyle and health risks can significantly lower dementia risk in people with one or no APOE ε4 alleles. However, individuals carrying two APOE ε4 alleles may require different preventive or therapeutic approaches.
New AI algorithms demonstrate improved accuracy in evaluating radiographic data and assessing joint inflammation. These innovations include the RADAR algorithm, ADMIRA, and thermography-based systems, offering promising alternatives to traditional imaging methods.
A new study found that sewage overflows in homes can introduce antibiotic-resistant and multidrug-resistant bacteria, making infections difficult to treat. The research collected samples from 86 Maryland homes and found nearly half had E. enterococci present, with over a third harboring antibiotic-resistant strains.
A systematic review of 73 studies found that early diet may shape cognitive performance and academic outcomes in adolescents. Unhealthy dietary patterns in infancy have lasting consequences for intelligence in adolescence, according to the study.
A new method for sequencing hantaviruses improves on existing strategies by generating whole-genome data from low-viral concentration samples. The approach, developed by Janet Manson and colleagues, has already proven useful in the field and shows promise for expanding to other viruses.
Research in flies shows that tumor cells with chromosomal instability can become senescent and release signals altering neighboring tissue behavior. This process promotes tumor growth by inducing the death of nearby healthy cells.
Researchers have discovered a new subtype of foam cells that form in early atherosclerosis, driven by mechanical stacking stress. These coralthelial cells promote inflammation and accelerate lesion development. The study offers promising therapeutic targets and novel prevention strategies for cardiovascular disease prevention.
A recent study published in Development reveals that the UTY gene on the human Y chromosome still contributes to transcriptional regulation during early development. Despite its low expression and reduced enzymatic activity, UTY co-occupies active regulatory elements with its X chromosome homolog UTX.
Researchers developed a multifunctional protective layer to overcome limitations of high-capacity, lithium-rich Mn-based oxide (LRMO) materials. The new cathode achieves exceptional fast-charging capability, long-term cycling stability, and high energy density with minimal Sc consumption.
The updated ASAS-SPARTAN revised classification criteria for axSpA prioritize MRI of the sacroiliac joints and incorporate a focused set of clinical variables. The new recommendations also emphasize the role of imaging in diagnosing and managing both axial and peripheral SpA.
A new study has discovered a crucial protein interaction that controls the photosynthetic machinery in plants. The discovery sheds light on how plants adapt to changes in light conditions and balance the light-harvesting capacities of both photosystems, enabling efficient energy transformation.
Researchers developed a new method to observe nanoscale spin waves, directly detecting short-wavelength magnons using resonant soft X-rays. The technique, called magnon momentum microscopy (MMM), reveals strong nonlinear interactions and four-magnon scattering processes in magnetic materials.