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Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.

Optogenetic therapy safe, shows signs of vision restoration in patients with advanced retinitis pigmentosa, according to international study led by Pitt scientists

Researchers at the University of Pittsburgh and international collaborators have developed an optogenetics-based treatment that improved visual function in some patients with advanced retinitis pigmentosa. The treatment, which combines gene therapy and visual stimulation, showed encouraging results in tests of safety and efficacy.

SourceUniversity of Pittsburgh·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial

Optogenetic therapy is safe and allows blind people to detect objects

A new study demonstrates the safety and efficacy of optogenetic therapy for advanced retinitis pigmentosa, with 6 of 8 patients showing clinically meaningful improvements in visual tasks. The treatment, which combines gene therapy and light-stimulating goggles, enables blind individuals to detect objects and navigate their environment.

SourceInstitute of Molecular and Clinical Ophthalmology Basel·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial

700,000-year-old elephant tooth reveals a lost ecosystem shared by early humans in the levant

Researchers reconstruct a lush landscape of woodlands, wetlands, and waterways from the Pleistocene, inhabited by giant elephants and early toolmakers. The findings provide a rare glimpse into the environment shared by early humans and giant elephants, shedding light on human origins and the forces that shaped our species.

SourceTel-Hai University of Kiryat Shmona in the Galilee·JournalQuaternary Science Reviews·TypeObservational study

Of mice and zebrafish: how MSK scientists solved a decades-old mystery and uncovered new insights about inflammation

Researchers at Memorial Sloan Kettering Cancer Center identify a critical inflammatory signaling pathway and its role in protecting healthy cells from immune response damage. The discovery opens new avenues for understanding diseases where inflammation runs amok, including cancer, inflammatory bowel disease, and asthma.

SourceMemorial Sloan Kettering Cancer Center·JournalNature·TypeExperimental study

Elevated lipoprotein(a) is associated with the progression of carotid atherosclerosis

Elevated lipoprotein(a) levels are associated with the progression of carotid atherosclerosis in East Asian populations. Participants with high Lp(a) levels (>50 mg/dL) had a higher risk of developing carotid plaques and faster progression to carotid stenosis, highlighting the importance of measuring Lp(a) for risk stratification.

SourceNational Cerebral and Cardiovascular Center·JournalEuropean Journal of Preventive Cardiology

Research Spotlight: What the Nurses’ Health Studies have illuminated about women’s health over the past five decades

The Nurses' Health Studies have provided a unique opportunity to prospectively follow large populations of women over decades, studying the impact of diet, lifestyle, and other factors on health. The studies have generated evidence that has shaped clinical guidelines and public health recommendations, with findings supporting recommend...

SourceMass General Brigham·JournalThe Lancet·TypeRandomized controlled/clinical trial

Could your epilepsy medication affect your birth control?

Researchers found nearly one-third of people prescribed hormonal contraceptives were also prescribed antiseizure medications that can reduce contraceptive effectiveness. The study suggests many people may be prescribed combination medications that could decrease hormonal contraceptive effectiveness and increase the risk of unintended p...

SourceAmerican Academy of Neurology·JournalNeurology

AI could make cardiac MRI reports easier for patients to understand

A prospective real-world study evaluates the feasibility of AI models GPT-5.2 and DeepSeek-V3.2 for simplifying cardiac MRI reports. The results show that these AI models can significantly improve patient comprehension, with no significant differences in performance between the two models.

SourceCompuscript Ltd·JournalCardiovascular Innovations and Applications

Faster, sharper, easier imaging with “self-blinking dyes”

Researchers have developed a new approach using self-blinking dyes to enhance super-resolution microscopy, improving labelling accuracy and imaging efficiency. This method enables more straightforward and accessible imaging, reducing the barrier to entry for researchers not experienced in microscopy.

SourceUniversity of Göttingen·JournalNano Letters·TypeExperimental study

metaphactory by Digital Science now available on SAP® Store

metaphactory by Digital Science delivers a seamless, AI-ready Knowledge Graph experience to SAP customers, enabling them to model, explore, and build AI applications on enterprise data. With this integration, customers can build and manage their own custom knowledge layer on top of their enterprise data.

LSU Health New Orleans recruits internationally recognized leader to establish institution’s first academic department of radiation oncology

Dr. Iyengar will lead the development of an academic program integrating patient care, education, and research, expanding access to advanced treatments and clinical research. The new department will strengthen collaboration among radiation oncologists, medical oncologists, and other specialists to develop more precise and effective tre...

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