Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
A Korean research team has developed NUDGE, a foundational technology that redirects cell fate in a desired direction through a minimal, temporary intervention. The approach harnesses the gene regulatory dynamics already present within cells, allowing for a single temporary stimulus to guide a cell to a desired state. NUDGE's technolog...
Researchers found fossilized vomit pellets from plesiosaurs in river delta sediments, indicating they ate shellfish from the seafloor before vomiting. The fossils were compacted and covered in mucus, surviving the waves and tides.
A pooled data analysis of 51 prospective cohort studies found that higher ultra-processed food (UPF) intake is associated with greater risks of multiple chronic health issues, including cardiovascular events, cancer, obesity, metabolic syndrome/diabetes, and death. Consuming extra 100g of UPFs correspondsingly increases risks.
SourceBMJ Group·JournalFamily Medicine and Community Health·TypeMeta-analysis
A 30-day course of benznidazole taken once a day has been shown to significantly reduce side effects and improve treatment adherence for people with chronic chagas disease. The treatment, which is less toxic and easier to follow than the current standard regimen, was found to be non-inferior to the 60-day standard regimen.
A UK clinic's data suggests non-prescribed ketamine use among under-16s starts at age 13, with attendees more likely to live in socioeconomically deprived neighbourhoods and have experience of the care system. Heavy ketamine use is rising in the UK, with 8.4% in treatment now reporting ketamine use.
SourceBMJ Group·JournalArchives of Disease in Childhood·TypeCommentary/editorial
A new treatment for chagas disease has been found to be safer and more practical with once-daily dosing, reducing side effects by nearly 40% and improving treatment adherence. The 30-day benznidazole regimen is as effective as the standard 60-day treatment and has the potential to increase treatment completion rates.
A nationwide study in Denmark found that cancer incidence is 12% higher among men with type 2 diabetes and 22% higher among women with type 2 diabetes compared to those without diabetes. Obesity-related cancers, such as colorectal and postmenopausal breast cancer, are particularly prevalent among people with type 2 diabetes.
The Salk Institute's $18 million Bezos Earth Fund grant will test whether deeper-rooted soybeans can store more carbon in soil and withstand drought and disease. The project aims to develop and test soybean plants with deeper, stronger roots using artificial intelligence, field trials, and soil carbon studies.
Researchers found that repeated patterns in the environment can interfere with the algorithms and artificial intelligence models that estimate the distance between a camera and an object. This can cause an obstacle to appear significantly closer or farther away than it really is, posing a safety risk for autonomous systems.
Researchers at UTMB propose the 'frustration brake failure' hypothesis, suggesting frustration may play a key role in substance use disorders alongside craving, impulsivity, and habit. The concept suggests that repeated drug use may disrupt the relationship between frustration and motivation, leading to continued drug-seeking behavior.
A systematic review of 69 academic articles found 91.3% of authors had at least one food industry tie, highlighting the need for transparency in nutrition research. The study underscores the importance of considering industry relationships when evaluating debates over ultra-processed foods.
The 2026 Global Impact Conference focused on rebuilding evidence generation for drug development in rare diseases, neurology, and pediatrics. Key findings emphasized the importance of digital health technologies, patient experience, and emerging technologies in shaping the next decade of drug development.
C-Path's Translational Therapeutics Accelerator has awarded $1.7 million across five bridge grants for research in brain health, pediatrics, and rare diseases. The grants aim to advance small molecule, protein-based, and gene therapy candidates for conditions where existing options fall short.
The PATHFINDER 2 study found that adding a blood test to standard screening increased cancer detection 6.5-fold, identifying cancers with no routine screening options. The test demonstrated a high specificity and low false-positive rate, making it a powerful complement to standard screening.
NJIT students' swarm robot power plan, known as OSEHS, aims to harness 0.01% of the Sun's raw power to power the moon's surface. The team's proposal earned a $15,000 NASA prize and now plans to turn the idea into a startup venture to help power data centers.
Dr. Laura Kim's team aims to detect early-stage endometriosis using a quantum sensing platform, providing a new diagnostic tool for a debilitating inflammatory disease affecting 1 in 10 women. The technology, developed with a NIH Trailblazer Award, will measure subtle magnetic signals at the microscopic level, enabling earlier and more...
A new study by the Woods Hole Oceanographic Institution found that climate change may be more challenging for species to adapt to than previously thought, a new study suggests. The study of black-browed albatrosses found that limiting greenhouse gas emissions can improve the species' chances of survival, reducing projected extinction p...
New research suggests that social media is not a substitute for real-life emotional support, with study findings indicating a strong link between loneliness and poor mental health. The studies also found that social media use soon after waking was associated with depression.
A new study by UC Riverside scientists has identified MAPK14, a brain protein, as the driving force behind neuroHIV damage, which causes dementia, neuropathy, and memory problems. By targeting this protein, researchers hope to develop a treatment for neuroHIV, a condition affecting millions worldwide.
A new AI framework developed by NYU Tandon researchers combines traffic forecasting, spatial mapping, and a locally hosted large language model to provide actionable guidance for urban planners. The system outperformed conventional statistical forecasting techniques and demonstrated improved prediction accuracy on previously unseen data.
A new study suggests that combining human and algorithmic approaches can help the FDA prioritize medical device reviews, reducing recalls and improving efficiency. The system identifies potential safety risks and flags devices that require human expert review, allowing the FDA to focus on the most critical cases.
Researchers developed a model of the primary visual cortex, introducing feedback mechanisms to constrain chaos and reduce neural activity variability. The model showed a 93 percent reduction in variability, allowing the brain to remain flexible while reliably processing visual information.
Researchers found that mice moved closer to a familiar companion when hearing a warning signal, but not with a stranger. This suggests a brain circuit that links social memory to threat response, with the hippocampus acting as a gatekeeper for familiar interactions.
SourceVirginia Tech·JournalNeuropsychopharmacology·TypeExperimental study
The study highlights the fragmented timing of warming increases across the globe, providing a nuanced perspective on global-warming acceleration. Regional accelerations are most prominent in the Northern Hemisphere's mid-latitudes, such as southeast China and the Gulf of Mexico.
Researchers at UC San Diego identified a naturally occurring peptide called catestatin (CST) that reduces toxic protein accumulation, neuroinflammation, and improves cognitive function in mouse models. CST may provide a new peptide-based therapeutic strategy for Alzheimer's disease and related neurodegenerative disorders.
A new study from Florida International University found that preschoolers with a higher body mass index (BMI) showed differences in brain regions involved in reward, taste, and hunger. The study suggests that the relationship between obesity risk and brain development may begin years earlier than previously thought.
Researchers tested a potential drug combination for metastatic uveal melanoma, uncovering clues about treatment resistance. The study found that levels of an enzyme called ALDH1A3 increased after treatment in patients whose disease progressed, while those whose disease remained stable had lower levels.
Researchers at Thomas Jefferson University found that women with high smoking histories and previous cancer diagnoses were more likely to be overdue for breast cancer screening. Integrating a simple reminder into lung cancer screening programs can address the 'critical gap in preventive care', increasing adherence to recommended screen...
Researchers found a mathematical solution describing how a spin glass transitions to ultrafast behavior resembling a black hole. The discovery connects ultraslow quantum magnetism to fast, entangled dynamics, with potential applications in quantum technologies.
Three teams from Bangladesh, Indonesia, and Thailand won the hackathon with innovative digital health platforms and decision-support tools to support maternal and child nutrition. The winning teams will participate in the Asia-Pacific Global Health Innovation Hackathon Incubation Programme to further develop their ideas.
A startup collaboration between Silly Surfacing and the University of Pittsburgh's IDEA Lab has led to the development of a pothole-filling robot, utilizing 3D scanning, mapping, and computer vision to repair road damage. The system uses a time-of-flight camera and can fill a pothole at full scale.
Researchers found that three simple cleaning methods, including dishwashing liquid, 70% alcohol, and peracetic acid, substantially reduced bacterial levels on used single-use medical devices. The study suggests that these methods could be useful in emergency situations where medical supplies are scarce.
Researchers developed a system-level simulation framework to evaluate ultra-dense indoor 5G and 6G wireless networks, integrating 3GPP channel modeling, beamforming, and link adaptation. The framework achieved 42% higher average cell throughput and 160% higher 5th-percentile user throughput under imperfect channel information.
SourceELSP·TypeExperimental study
Insilico Medicine will present initial Phase I data for ISM6331, a pan-TEAD inhibitor, in patients with advanced solid tumors and mesothelioma. The treatment targets the Hippo pathway, a key regulator of cell growth and survival.
Researchers developed an AI-based method to predict bitterness of peptides, enabling de novo design of bitter peptides for improved flavor control. The method used a combination of a protein language model and an artificial neural network to analyze structural data, resulting in the identification of new bitter-tasting peptides.
A research team led by Professor Inki Kim has developed an ultra-sensitive nanoplasmonic biochip that verifies the efficacy of Parkinson's disease treatments in real time. The technology combines a stem cell-derived 'mini-brain' with a nanoplasmonic sensor to measure dopamine levels without damaging the tissue.
Researchers developed a 3D-printed copper mirror with built-in water-cooling channels for high-power 10.6-μm CO2 lasers. The integrated design improves laser-damage resistance and reduces heat buildup, enabling compact thermal-management solutions for EUV lithography and other high-power systems.
The book explores diverse microbial strategies for wastewater remediation, including indigenous microorganisms and genetically modified microorganisms. Advanced technologies such as biosorption and membrane bioreactors are also examined, highlighting their potential to address the growing global challenge of wastewater pollution.
This book examines the gut-brain axis and its influence on neurological health, including Alzheimer's, Parkinson's, and ALS. The authors discuss potential microbiota-based interventions, such as probiotics and prebiotics, to modulate neurological health.
The book delves into practical approaches to reducing waste and improving environmental performance in the tourism sector, covering topics such as food waste, plastic and e-waste, and eco-friendly hospitality. It emphasizes policy-driven solutions to promote responsible tourism development.