Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
A new treatment, extended aldosterone synthase inhibition (EASI), has been shown to reverse excess aldosterone production and lower blood pressure in people with primary aldosteronism. The treatment, which involves taking a new class of drugs for 6-12 months, has been found to sustain its benefits for up to two years after treatment en...
A global phase 3 clinical trial, ZEUS, tested a drug targeting interleukin-6, but found no reduction in cardiovascular event rates compared to placebo. The study's neutral findings suggest moving upstream to find the right target, while acknowledging the effectiveness of downstream IL-6 inhibition in modifiable earlier stage disease.
SourceMass General Brigham·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial
A new study has found that routine invasive procedures for stable heart disease do not improve long-term survival compared to drug therapy alone. The study, which followed over 5,000 patients with stable coronary artery disease, revealed that early invasive procedures eased symptoms and improved quality of life but did not reduce the r...
UT MD Anderson and P-Cure collaborate on a compact upright proton and helium ion therapy platform, combining expertise in radiation oncology and particle therapy. The alliance aims to establish the clinical value of helium ion therapy and advance the platform's capabilities.
Researchers found that charged states on carbon nanotubes, known as trions, retain their chirality, which is crucial for manipulating light and electric current in nanotechnology. This discovery opens new paths for quantum optics and potential applications in next-gen optoelectronic devices.
A randomized controlled trial found that Tai Chi Qigong and an exercise class improved sleep quality in older male cancer survivors, with no significant difference between the two. While the changes were modest, the study suggests that a more diverse range of participants and future studies are needed to confirm the findings.
SourceGenomic Press·JournalBrain Medicine·TypeRandomized controlled/clinical trial
A recent study published in Genomic Psychiatry analyzed the Alzheimer's Disease Neuroimaging Initiative and found that people with frequent anxiety scored lower on a standard test of global cognition. The authors suggest that a single serotonin receptor may be responsible for both worry and cognitive decline in Alzheimer's disease.
The employment-to-population ratio for people with disabilities held near record highs at 39.9% in October, reflecting sustained labor market growth. The employment-to-population ratio for people without disabilities also increased slightly, while labor force participation rates for people with disabilities decreased slightly.
Researchers at Texas A&M AgriLife Research used an AI tool to screen 1,100 human mitochondrial proteins for likely interactions, revealing nearly 2,900 new pairs. The study provides clues about the functions of mystery mitochondrial proteins and their roles in human diseases.
A University at Buffalo-led team has predicted the optical fingerprints of known atomic defects in hexagonal boron nitride, a material with potential applications in quantum technologies. The researchers' computer models simulated how different defects affect the intensity and polarization of light produced when h-BN is hit with a laser.
Researchers found that stock market analysts generally fail to adjust their price targets after Fed meetings, resulting in increased prediction inaccuracy. The study highlights potential limitations in how capital market intermediaries interpret and act upon macroeconomic information.
Alliance Clinical Trials is advancing early detection, improving treatments, and enhancing survivorship for lung cancer patients. The organization is conducting seven active clinical trials focused on prevention, early detection, treatment, and survivorship.
A Mount Sinai study found a single amino acid difference between rodent- and human-derived Andes virus isolates affects viral protein processing and release in human cells. The change enables faster virus-like particle release and altered protein behavior, providing a starting point for studying the virus's biology.
Researchers developed new instruments to assess empathy and Theory of Mind in everyday life, including positive and negative social contexts. The tools, EmpaToM-pos and EmpaToM-embarrass, provide a more precise understanding of human social understanding and its applications in clinical practice.
A new AI and biological data-driven approach revolutionizes urban water safety by tracking behavioral and morphological changes in indicator organisms and metabolic biomarkers. The framework prioritizes potential risk factors, enabling actionable priorities for management and shifting from reactive cleanup to predictive resilience.
Scientists have found that certain immune cells in fat tissue may protect against obesity-related inflammation in females, but contribute to harmful metabolic changes in males. The study identified six distinct eosinophil populations in adipose tissue, each with different gene-expression patterns and potential functions.
New research published in JAMA Network Open finds that anticholinergic medications for overactive bladder do not carry a greater long-term risk of dementia compared to beta-3 agonists. The study suggests that overactive bladder itself may be an early warning sign of neurodegenerative processes associated with dementia.
A review examines emotion perception, emotional learning and memory, and advances in brain-based affective computing. It discusses how emotional significance is learned and how emotion influences memory, highlighting the roles of brain regions and computational methods used to identify emotion.
Researchers developed a new method to produce ruthenium single-atom catalysts with high ruthenium content, achieving up to 11% by weight, and demonstrated excellent CO2 conversion efficiency and selectivity. The catalyst maintained its performance after repeated use, showing promise for efficient and sustainable chemical production.
A shape-adaptive hydrogel, iHEÄLS, has been developed for complex trauma reconstruction, offering a versatile platform for challenging clinical scenarios. The material combines rapid haemostasis, strong tissue adhesion, self-healing capability and mechanical resilience.
Researchers discovered tiny melt traces in an ancient rock from the Colorado Plateau, providing new insights into the region's geological history. The study suggests that hot magma carried the rock upward, heating it before it cooled and was brought to the surface by a later explosive event.
Researchers built a warm-white OLED from a single-dopant light-emitting molecule, producing 27.1% external quantum efficiency, nearly double the previous ceiling. The device achieved high efficiency and durability, with a long operating lifetime and reduced efficiency roll-off.
Researchers at Tohoku University developed a mechanical reflex module that reproduces the patellar tendon reflex in robots, enabling bipedal walking. The module combines sensing, computation, and actuation within its physical structure, reducing system complexity and computational demands.
Senescence is a complex process that contributes to chronic inflammation and disease progression. Emerging drug delivery technologies, such as polymer-based nanocarriers and cell-based delivery systems, offer precise and controllable therapeutic strategies for modulating senescence and targeting senescent cells.
Researchers developed an electret-mediated dual-functional strategy to create organic single crystals that can sense, store and process polarized light information. The device reached a dichroic ratio of 2,920, significantly higher than the intrinsic limit, and demonstrated synaptic-like behavior.
Researchers at Xi'an Jiaotong University found that immersion heating delivers the fastest warm-up, while boiling-based immersion systems effectively prevent thermal runaway propagation. Immersion cooling also slows capacity fade, but with trade-offs in pumping power and upfront cost.
Researchers are exploring how controlling electron spin in catalysts can improve chemical reactions. Studies show that 53% of electrocatalysis studies suggest changes in electron spin as the main reason for improved performance. However, more evidence is needed to confirm this.
Insilico Medicine releases Longevity Grok, a 24/7 AI system that unifies personal health records, tracks biological analysis, and provides personalized lifestyle interventions. The system also drives communal AI-powered geroscience research and features a zero-trust architecture for data privacy.
Researchers designed hard carbon materials with different pore structures using lignin precursors, revealing that smaller pores facilitate sodium-ion storage performance. The study provides theoretical guidance for designing high-performance HC anodes, enabling long cycling life of sodium-ion batteries.
A study published in Nature Medicine reveals that artificial intelligence can identify associations between human movement patterns and 1,887 health measures spanning 18 body systems. Movement analysis provided independent predictive information beyond traditional health assessments.
SourceBrightPoint·JournalNature Medicine·TypeImaging analysis
Researchers developed a 4+1 strategy integrating DFT, KMC, DMC, and flowsheet synthesis to predict thermogelling polymer behavior across scales. The approach predicts kinetic stages, condensed states, and thermogellability with artificial intelligence, establishing a fundamental methodology for ab initio molecular engineering.
Synchrotron X-ray scattering can follow perovskite films from formation to device failure, revealing the impact of halide composition, ageing, and spatial heterogeneity. The review provides a practical guide for experimental choices and methodological limitations.
Insilico Medicine CEO Dr. Alex Zhavoronkov and President Dr. Alex Aliper will speak at the FT Healthcare Summit and Revive ME 2026 about longevity medicine and generative biology. They will discuss the company's translational path, evidence standards, and regulatory frameworks for longevity medicine.
Researchers have developed a highly efficient blue OLED material with improved stability and resistance to concentration quenching. The material, SAF-BO, uses a multi-spiro molecular design strategy that effectively regulates molecular packing and suppresses aggregation-caused quenching and bimolecular exciton annihilation.
Researchers review how AI enhances continuous glucose monitoring to enable predictive, personalized diabetes management, improving glycemic outcomes and prioritizing high-risk patients. Machine learning models forecast individualized responses to meals, enabling tailored dietary and physical activity guidance.
A new study reveals sharp declines in PFOS and PFOA emissions in China, with emissions falling by 89% and 99% respectively, but hotspots persist in the Bohai Rim, Yangtze River Delta, and Pearl River Delta.
The Quantum Biology Laboratory at Howard University publishes a landmark review on 'Quantum Biology 2.0', highlighting the field's shift to whole-biosystems integrated approaches. Researchers discover superradiance in solvated protein fibers, revealing a new window into the role of quantum processes in biological systems.
The Phase 2 trial will evaluate the efficacy and safety of OYE-101 in adult surgical patients, aiming to accelerate emergence from general anesthesia and improve postoperative recovery. The trial is expected to enroll approximately 40 patients and will assess time to emergence, sedation, and alertness, as well as postoperative recovery...
Preprints.org hosted a webinar on the cost of knowledge, discussing human and environmental costs driven by private interests. The event highlighted the role of preprints in addressing these issues and lowering barriers to sharing knowledge.
Scientists have discovered that cardiac aging is not evenly distributed throughout the heart, with hotspots of inflammation and scarring concentrated in the valves and aortic root. These regions may serve as hubs of cardiac aging, influencing surrounding muscle tissue.